Jakub Staroń

Jakub Staroń, MSc

e-mail: staron@if-pan.krakow.pl

phone: +4812 66 23 320

 

 

 

Research interests:

Scientific career:

 

 

Participation in research projects:

  • EXtention of academia-based PLATFORM to antidepressant hits discovery (PLATFORMex), Pol-Nor/198887/73/2013, function: executor, 2013 –
  • Innovative therapies for neurodegenerative and neurodevelopmental diseases based on mGlu receptor allosteric modulators – Allosterix, NCBiR 178469, function: executor, 2013 –
  • Demeter – Depression – mechanisms – therapy, WND-POIG.01.01.02-12.004/09 (http://www.de-me-ter.pl), function: executor, 2010-2014.
  • Allosteric modulation – new strategy in pharmacotherapy. Identification of the psychotropic properties of glutamatergic receptor ligands of group III. WND-POIG.01.03.01-12-100/08 (http://modall.pl), function: executor, 2011-2012.
  • Creating an academia-based platform to discover substances acting on serotonergic or glutamatergic systems as potential new antidepressant or anxiolytic drugs. PNRF-103-AI-1/07 (http://cns-platform.eu/main.html), function: executor, 2010-2011.
  • Antagonists of 5-HT6 receptor as advanced antipsychotic drugs with procognitive properties, UDA-POIG.01.03.01-12-063/09-02 (http://www.prokog.pl), function: executor, 2010-2013.

Scientific reports:

a) posters:

  1. Rugor, A.; Mordalski, S.; Staroń, J.; Bojarski, A. ; Szaleniec, M.; Steroid C25 Dehydrogenase – homology modeling and substrate spectrum; Molybdenum & Tungsten Enzymes Conference, 16-19.07.2013, Sintra, Portugal, Book of Abstracts.
  2. A. Rugor, S. Mordalski, J. Staroń, M. Tataruch, A. Bojarski, M. Szaleniec: Pozyskiwanie bakteryjnego katalizatora dehydrogenazy C-25 steroidowej i synteza 25-hydroksysteroli; 56 Zjazd Naukowy PTChem i SITPChem, 16-20.09.2013, Siedlce, Poland
  3. Staroń, J.; Warszycki, D.; Kalinowska-Tłuścik, J.; Satała, G.; Bojarski, A.J.; The use of bioisosteric strategy to design and analyse 5-HT6 ligands binding mode;  III Konferencja Naukowa Doktorantów Wydziału Lekarskiego i Farmaceutycznego UJ CM, 09-10.05.2013, Zeszyty Naukowe Towarzystwa Doktorantów Uniwersytetu Jagiellońskiego, Nauki Ścisłe, Nr 6 (1/2013), p.164. Poster
  4. A. Rugor, S. Mordalski, J. Staroń, A. Bojarski, M. Szaleniec: Homology Modeling of Steroid C25 Dehydrogenase, 5-th Central European Congress of Life Sciences EUROBIOTECH 2013, 08-11.10.2013, Kraków, Poland
  5. Warszycki, D.; Satała, G.; Staroń, J.; Bojarski, A.J.; Bioisosteric replacement in search for novel 5-HT6R ligands; 5th Symposium of the Polish Bioinformatics Society, 25-27.05.2012, Gdańsk, Poland, Book of Abstracts, p.Talk19. Abstract Poster
  6. Brański, P.; Staroń, J.; Bugno, R.; Wierońska, J.; Bojarski, A.J.; Burnat, G.; Pałucha-Poniewiara, A.; Pilc, A.; Synthesis and characterization of novel metabotropic glutamate receptor 2/3 (mGluR2/3) positive allosteric modulator (PAM); The Twentieth Days of Neuropsychopharmacology, 22-25.05.2011, Ustroń-Jaszowiec,Poland, Pharmacological Reports, 2011, 63, p.577.
  7. Staroń, J.; Warszycki, D.; Satała, G.; Bugno, R.; Bojarski, A.J.; Bioisosterism, the use in designing 5-HT6 receptor ligands; 4th International Symposium on Advances in Synthetic and Medicinal Chemistry, 21-25.08.2011, St. Petersburg, Russia, Book of Abstracts, p.176. Abstract Poster
  8. Brański, P.; Staroń, J.; Bugno, R.; Wierońska, J.; Bojarski, A.; Burnat, G.; Chorobik, P.; Chruścicka, B.; Pałucha-Poniewiara, A.; Sławińska, A.; Stachowicz, K.; Pilc, A.; Discovery of novel and systemically active allosteric ligand of metabotropic glutamate receptor group II with potential anxiolytic properties; 4th International Symposium on Advances in Synthetic and Medicinal Chemistry, 21-25.08.2011, St. Petersburg, Russia,  Book of Abstracts.
  9. Brański, P.; Bojarski, A.; Burnat, G.; Chorobik, P.; Bugno, R.; Kurczab, R.; Staroń, J.; Chruścicka, B.; Pałucha-Poniewiara, A.; Pilc, A.; Searching for a new potential mGluR4 positive allosteric modulators; 7th International Meeting on Metabotropic Glutamate Receptors, 02-07.10.2011 Taormina, Italy, Curr. Neuropharmacol., 2011, 9, Suppl. 1.