Publications 2013

1. Warszycki, D.; Mordalski, S.; Kristiansen, K.; Kafel, R.; Sylte, I.; Chilmonczyk, Z.; Bojarski, A. J. A Linear Combination of Pharmacophore Hypotheses as a New Tool in Search of New Active Compounds – An Application for 5-HT1A Receptor Ligands. PLoS. One. 2013, 8, e84510 (http://www.ncbi.nlm.nih.gov/pubmed/24367669)
2. Kurczab, R.; Bojarski, A. J. New Strategy for Receptor-Based Pharmacophore Query Construction: A Case Study for 5-HT7 Receptor Ligands. J. Chem. Inf. Model. 2013, 53, 3233-3243 (http://www.ncbi.nlm.nih.gov/pubmed/24245803)
3. Smusz, S.; Kurczab, R. ; Bojarski, A. J. A multidimensional analysis of machine learning methods performance in the classification of bioactive compounds. Chemometr. Intell. Lab. Syst. 2013, 128, 89-100 (http://www.sciencedirect.com/science/article/pii/S0169743913001561)
4. Popieralska, H.; Myka, A.; Drabińska, B.; Gruszeczka, A.; Kruk, J.; Kurczab, R.; Kujawski, J. Pyrazole derivatives. A challenge of modern academic and industrial chemistry. Przem. Chem. 2013, 92, 905-914.
5. Waszkielewicz, A. M.; Gunia, A.; Szkaradek, N.; Pytka, K.; Siwek, A.; Satala, G.; Bojarski, A. J.; Szneler, E.; Marona, H. Synthesis and evaluation of pharmacological properties of some new xanthone derivatives with piperazine moiety. Bioorg. Med. Chem. Lett. 2013, 23, 4419-4423 (http://www.ncbi.nlm.nih.gov/pubmed/23787101)
6.  Lacivita, E.; De Giorgio, P.; Patarnello, D.; Niso, M.; Colabufo, N. A.; Berardi, F.; Perrone, R.; Satala, G.; Duszynska, B.; Bojarski, A. J.; Leopoldo, M. Towards metabolically stable 5-HT receptor ligands: a study on 1-arylpiperazine derivatives and related isosters. Exp. Brain Res. 2013, 230, 569-582 (http://www.ncbi.nlm.nih.gov/pubmed/23571499)
7. Gabrielsen, M.; Wolosewicz, K.; Zawadzka, A.; Kossakowski, J.; Nowak, G.; Wolak, M.; Stachowicz, K.; Siwek, A.; Ravna, A. W.; Kufareva, I.; Kozerski, L.; Bednarek, E.; Sitkowski, J.; Bocian, W.; Abagyan, R.; Bojarski, A. J.; Sylte, I.; Chilmonczyk, Z. Synthesis, Antidepressant Evaluation and Docking Studies of Long-Chain Alkylnitroquipazines as Serotonin Transporter Inhibitors. Chem. Biol. Drug Des 2013, 81, 695-706 (http://www.ncbi.nlm.nih.gov/pubmed/23574807)
8. Kowalski, P.; Mitka, K.; Jaskowska, J.; Duszynska, B.; Bojarski, A. J. New Arylpiperazines with Flexible versus Partly Constrained Linker as Serotonin 5-HT1A /5-HT7 Receptor Ligands. Arch. Pharm. (Weinheim) 2013, 346, 339-348 (http://www.ncbi.nlm.nih.gov/pubmed/23609855)
9. Smusz, S.; Kurczab, R. ; Bojarski, A. J. The influence of the inactives subset generation on the performance of machine learning methods. J. Cheminform. 2013, 5, 17 (http://www.ncbi.nlm.nih.gov/pubmed/23561266)
10. Wrobel, M. Z.; Chodkowski, A.; Herold, F.; Gomolka, A. ; Kleps, J.; Mazurek, A. P.; Plucinski, F.; Mazurek, A.; Nowak, G.; Siwek, A.; Stachowicz, K.; Slawinska, A.; Wolak, M.; Szewczyk, B.; Satala, G.; Bojarski, A. J.; Turlo, J. Synthesis and biological evaluation of novel pyrrolidine-2,5-dione derivatives as potential antidepressant agents. Part 1. Eur. J. Med. Chem. 2013, 63, 484-500 (http://www.ncbi.nlm.nih.gov/pubmed/23524160)
11. Chlon-Rzepa, G.; Zmudzki, P.; Satala, G.; Duszynska, B.; Partyka, A.; Wrobel, D.; Jastrzebska-Wiesek, M.; Wesolowska, A.; Bojarski, A. J.; Pawlowski, M.; Zajdel, P. New 8-aminoalkyl derivatives of purine-2,6-dione with arylalkyl, allyl or propynyl substituents in position 7, their 5-HT1A, 5-HT2A, and 5-HT7 receptor affinity and pharmacological evaluation. Pharmacol. Rep. 2013, 65, 15-29 (http://www.ncbi.nlm.nih.gov/pubmed/23563020)
12. Grychowska, K.; Marciniec, K.; Canale, V.; Szymiec, M. ; Glanowski, G.; Satala, G.; Maslankiewicz, A.; Pawlowski, M.; Bojarski, A. J.; Zajdel, P. Quinolinesulfonamides of Aryloxy-/Arylthio-ethyl Piperidines: Influence of an Arylether Fragment on 5-HT1A /5-HT7 Receptor Selectivity. Arch. Pharm. (Weinheim). 2013, 346, 180-188 (http://www.ncbi.nlm.nih.gov/pubmed/23381952)
13. Testa, B.; Bojarski, A. J.; Mordalski, S. Simulations in evolution. III. Randomness as a generator of opportunities. Chem. Biodivers. 2013, 10, 62-72 (http://www.ncbi.nlm.nih.gov/pubmed/23341208)
14. Czopek, A.; Kolaczkowski, M.; Bucki, A.; Byrtus, H.; Pawlowski, M.; Siwek, A.; Bojarski, A. J.; Bednarski, M.; Wrobel, D.; Wesolowska, A. Novel Mannich Bases, 5-Arylimidazolidine-2,4-dione Derivatives with Dual 5-HT(1A) Receptor and Serotonin Transporter Affinity. Arch. Pharm. (Weinheim). 2013, 346, 98-109 (http://www.ncbi.nlm.nih.gov/pubmed/23288448)
15. Obniska, J.; Chlebek, I.; Kamiński, K.; Bojarski, A. J.; Satala, G. Anticonvulsant Activity and 5-HT1A/5-HT7 Receptors Affinity of Piperazine Derivatives of 3,3-Diphenyl- and 3,3-Dimethyl-succinimides. Lett. Drug Des. Discov. 2013, 10, 173-182
16. Szafranski, P. W.; Dyduch, K.; Kosciolek, T.; Wrobel, T. P.; Gomez-Canas, M.; Gomez-Ruiz, M.; Fernandez-Ruiz, J.; Mlynarski, J. Design and Synthesis of Novel Cannabinoid Ligands Based on a 1,2,3- triazole Scaffold. Lett. Drug Des. Discov. 2013, 10, 169-172 (http://www.ingentaconnect.com/content/ben/lddd/2013/00000010/00000002/010aj?crawler=true)
17. Zajdel, P.; Marciniec, K.; Maslankiewicz, A.; Grychowska, K.; Satala, G.; Duszynska, B.; Lenda, T.; Siwek, A.; Nowak, G.; Partyka, A.; Wrobel, D.; Jastrzebska-Wiesek, M.;  Bojarski, A. J.; Wesolowska, A.; Pawlowski, M. Antidepressant and antipsychotic activity of new quinoline- and isoquinoline-sulfonamide analogs of aripiprazole targeting serotonin 5-HT(1A)/5-HT(2A)/5-HT(7) and dopamine D(2)/D(3) receptors. Eur. J. Med. Chem. 2013, 60, 42-50 (http://www.ncbi.nlm.nih.gov/pubmed/23279866)