Publications 2006

  1. Daniel, W. A.; Haduch, A.; Syrek, M.; Boksa, J. Direct and indirect interactions between antidepressant drugs and CYP2C6 in the rat liver during long-term treatment. Eur. Neuropsychopharmacol. 2006, 16, 580-587 ( .
  2. Kolaczkowski, M.; Nowak, M.; Pawlowski, M.; Bojarski, A. J. Receptor-based pharmacophores for serotonin 5-HT7R antagonists-implications to selectivity. J. Med. Chem. 2006, 49, 6732-6741 (
  3. Bojarski, A. J. Pharmacophore models for metabotropic 5-HT receptor ligands. Curr. Top. Med. Chem. 2006, 6, 2005-2026 (
  4. Obniska, J.; Kolaczkowski, M.; Bojarski, A. J.; Duszynska, B. Synthesis, anticonvulsant activity and 5-HT1A, 5-HT2A receptor affinity of new N-[(4-arylpiperazin-1-yl)-alkyl] derivatives of 2-azaspiro[4.4]nonane and [4.5]decane-1,3-dione. Eur. J. Med. Chem. 2006, 41, 874-881 (
  5. Paluchowska, M. H.; Bugno, R.; Charakchieva-Minol, S.; Bojarski, A. J.; Tatarczynska, E.; Chojnacka-Wojcik, E. Conformational Restriction in Novel NAN-190 and MP3022 Analogs and Their 5-HT(1A) Receptor Activity. Arch. Pharm. (Weinheim) 2006, 339, 498-506 (
  6. Zajdel, P.; Subra, G.; Bojarski, A. J.; Duszynska, B.; Pawlowski, M.; Martinez, J. Arylpiperazines with N-acylated amino acids as 5-HT(1A) receptor ligands. Bioorg. Med. Chem. Lett. 2006, 16, 3406-3410 (
  7. Bojarski, A. J.; Nowak, M.; Testa, B. Conformational Fluctuations versus Constraints in Amino Acid Side Chains: The Evolution of Information Content from Free Amino Acids to Proteins. Chem. Biodivers. 2006, 3, 245-273 (
  8. Obniska, J.; Tatarczynska, E.; Nikiforuk, A.; Charakchieva-Minol, S.; Duszynska, B. Synthesis and 5-HT(1A)/5-HT(2A) receptor activity of N-(4-arylpiperazin-1-yl)alkyl derivatives of 2-azaspiro([4.4]nonane and [4.5]decane-1,3-dione. Pharmacol. Rep. 2006, 58, 107-114 (
  9. Nowak, M.; Kolaczkowski, M.; Pawlowski, M.; Bojarski, A. J. Homology Modeling of the Serotonin 5-HT(1A) Receptor Using Automated Docking of Bioactive Compounds with Defined Geometry. J. Med. Chem. 2006, 49, 205-214 (
  10. Bojarski, A. J.; Paluchowska, M. H.; Duszynska, B.; Bugno, R.; Klodzinska, A.; Tatarczynska, E.; Chojnacka-Wojcik, E. Structure-intrinsic activity relationship studies in the group of 1-imido/amido substituted 4-(4-arylpiperazin-1-yl)cyclohexane derivatives; new, potent 5-HT(1A) receptor agents with anxiolytic- like activity. Bioorg. Med. Chem. 2006, 14, 1391-1402 (