Publications 2016

  1. Żmudzki, P.; Satała, G.; Chłoń-Rzepa, G.; Bojarski, A.J. Kazek, G.; Siwek, A.; Gryboś, A.; Głuch-Litwin, M.; Wesołowska, A.; Pawłowski, M. Structure-5-HT/D2 Receptor Affinity Relationship in a New Group of 1-Arylpiperazynylalkyl Derivatives of 8-Dialkylamino-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione, Arch. Pharm. (Weinheim). , 2016, (http://www.ncbi.nlm.nih.gov/pubmed/27510801)
  2. Zajdel, P.; Marciniec, K.; Satała, G.; Canale, V.; Kos, T.; Partyka, A.; Jastrzębska-Więsek, M.; Wesołowska, A.; Basińska-Ziobroń, A.; Wójcikowski, J.; Daniel, W. A.; Bojarski, A. J. Popik, P. N1-Azinylsulfonyl-1H-indoles: 5-HT6 Receptor Antagonists with Procognitive and Antidepressant-Like Properties. ACS Med Chem Lett. , 20167, 618-622 (http://www.ncbi.nlm.nih.gov/pubmed/27326337)
  3. Lacivita, E.; Podlewska, S.; Speranza, L.; Niso, M.; Satała, G.; Perrone, R.; Perrone-Capano, C.; Bojarski, A. J.; Leopoldo, M. Structural modifications of the serotonin 5-HT7 receptor agonist N-(4-cyanophenylmethyl)-4-(2-biphenyl)-1-piperazinehexanamide (LP-211) to improve in vitro microsomal stability: A case study, Eur. J. Med. Chem., 2016, 120, 363-379 (http://www.ncbi.nlm.nih.gov/pubmed/27318552)
  4. Kurczab, R.; Canale, V.; Zajdel, P.; Bojarski, A. J. An Algorithm to Identify Target-Selective Ligands – A Case Study of 5-HT7/5-HT1A Receptor Selectivit, PLoS One, 2016, 11, e0156986 (http://www.ncbi.nlm.nih.gov/pubmed/27271158)
  5. Staroń, J.; Warszycki, D.; Kurczab, R.; Satała, G.; Bugno, R.; Hogendorf, A.; Bojarski, A. J. Halogen bonding enhances activity in a series of dual 5-HT6/D2 ligands designed in a hybrid bioisostere generation/virtual screening protocol, RSC Adv., 2016, 6, 54918-54925 (http://pubs.rsc.org/en/content/articlelanding/2016/ra/c6ra08714k#!divAbstract)
  6. Gunia-Krzyzak, A.; Pytka, K.; Słoczyńska, K.; Waszkielewicz, A.M.; Satała, G.; Bojarski, A.J.; Sapa, J.; Filipek, B.; Cegła, M.; Pekala, E.; Marona, H. Preliminary evaluation of central nervous system activity of (E)-N-2-methyl-3-phenylprop-2-enyl ((E)-α-methylcinnamyl) derivatives of selected aminoalkanols, Acta Pol. Pharm., 20162, 345-357 (http://www.ncbi.nlm.nih.gov/pubmed/27180427).
  7. Zagórska, A.; Gryzło, B.; Satała, G.; Bojarski, A.J.; Głuch-Lutwin, M.; Mordyl, B.; Kazek, G.; Pawłowski, M. Receptor affinity and phosphodiesterases 4B and 10A activity of octahydro- and 6,7-dimethoxy-3,4-dihydro- isoquinolin-2-(1H)-yl-alkyl derivatives of imidazo- and pyrimidino[2,1-f]purines, Acta Pol. Pharm., 20162, 369-377 (http://www.ncbi.nlm.nih.gov/pubmed/27180429).
  8. Plebanek, E.; Chevrier, F.; Roy, V.; Garenne, T.; Lecaille, F.; Warszycki, D.; Bojarski, A.J.; Lalmanach, G.; Agrofoglio, L.A. Straightforward synthesis of 2,4,6-trisubstituted 1,3,5-triazine compounds targeting cysteine cathepsins K and S., Eur. J. Med. Chem., 2016, 121, 12-20 (http://www.ncbi.nlm.nih.gov/pubmed/27214508).
  9. Kucwaj-Brysz, K.; Warszycki, D.; Podlewska, S.; Witek, J.; Witek, K.; González Izquierdo, A.; Satała, G.; Loza, M.I.; Lubelska, A.; Latacz, G.; Bojarski, A.J.; Castro, M.; Kieć-Kononowicz, K.; Handzlik, J. Rational design in search for 5-phenylhydantoin selective 5-HT7R antagonists. Molecular modeling, synthesis and biological evaluation, Eur. J. Med. Chem., 2016, 112, 258-269 (http://www.ncbi.nlm.nih.gov/pubmed/26900658).
  10. Isberg, V.; Mordalski, S.; Munk, C.; Rataj, K.; Harpsøe, K.; Hauser, A.S.; Vroling, B.; Bojarski, A.J.; Vriend, G.; Gloriam, D.E. GPCRdb: an information system for G protein-coupled receptors. Nucleic Acids Res., 201644 (D1), D356-64  (http://www.ncbi.nlm.nih.gov/pubmed/26582914)
  11. Kubacka, M.; Mogilski, S.; Bednarski, M.; Nowiński, L.; Dudek, M.; Żmudzka, E.; Siwek, A.; Waszkielewicz, A.M.; Marona, H.; Satała, G.; Bojarski, A.; Filipek, B.; Pytka, K. Antidepressant-like activity of aroxyalkyl derivatives of 2-methoxyphenylpiperazine and evidence for the involvement of serotonin receptor subtypes in their mechanism of action, Pharmacol. Biochem Behav. 2016, 141, 8-41 (http://www.ncbi.nlm.nih.gov/pubmed/26647362)
  12. Canale, V.; Kurczab, R.; Partyka, A.; Satała, G.; Lenda, T.; Jastrzębska-Więsek, M.; Wesołowska, A.; Bojarski, A.J.; Zajdel, P. Towards new 5-HT7 antagonists among arylsulfonamide derivatives of (aryloxy)ethyl-alkyl amines: Multiobjective based design, synthesis, and antidepressant and anxiolytic properties, Eur. J. Med. Chem. 2016,108, 334-346 (http://www.ncbi.nlm.nih.gov/pubmed/26698537).
  13. Canale, V.; Kurczab, R.; Partyka, A.; Satała, G.; Słoczyńska, K.; Kos, T.;Jastrzębska-Więsek, M.; Siwek, A.; Pękala, E.; Bojarski, A.J.; Wesołowska, A.; Popik, P.; Zajdel, P. N-Alkylated arylsulfonamides of (aryloxy)ethyl piperidines: 5-HT7 receptor selectivity versus multireceptor profile, Bioorg. Med. Chem. 2016, 15, S0968-0896(15)30164-4 (http://www.ncbi.nlm.nih.gov/pubmed/26706111).
  14. Chłoń-Rzepa, G.; Bucki, A.; Kołaczkowski, M.; Partyka, A.; Jastrzębska-Więsek, M.; Satała, G.; Bojarski, A.J.; Kalinowska-Tłuścik, J.; Kazek, G.; Mordyl, B.; Głuch-Lutwin, M.; Wesołowska, A. Arylpiperazinylalkyl derivatives of 8-amino-1,3-dimethylpurine-2,6-dione as novel multitarget 5-HT/D receptor agents with potential antipsychotic activity. J. Enzyme Inhib. Med. Chem. 2016 (http://www.ncbi.nlm.nih.gov/pubmed/26406608)