Dawid Warszycki, MSc


 

e-mail: warszyc@if-pan.krakow.pl
phone: +4812 66 23 301

 

 

 Research interests:

  • computer aided drug design
  • pharmacophore modeling
  • bioisosterism
  • virtual screening
  • machine learning
  • homology modelling
  • GPCR

 

Scientific career:

  • 11.2018-06.2020 – employed in Selvita company on the Specialist II position, responsible for computed-aided drug design 
  • 12.2017, PhD in Pharmacy, Faculty of Pharmacy, Jagiellonian University Medicinal College
  • From 04.2014 – employed at the Institute of Pharmacology, Polish Academy of Sciences in Cracow, Department of Medicinal Chemistry, position: research assistant
  • 05.2010-04.2014 – employed at the Institute of Pharmacology, Polish Academy of Sciences in Cracow, Department of Medicinal Chemistry, position: engineering and technology.
  • 10.2008-06.2010 – second level studies, course: chemistry,  Institute de Chimie Organique at Analityque Universite d’Orleans, obtained degree: Master of Science (06.2012)
  • 10.2005-06.2010 – full-time master′s course, course: chemistry, Faculty of Chemistry of the Jagiellonian University in Cracow, obtained degree: Master of Science (06.2012)

Publications:

  1. Jakub Staroń, Ryszard Bugno, Wojciech Pietruś, Grzegorz Satała, Stefan Mordalski, Dawid Warszycki, Agata Hogendorf, Adam S. Hogendorf, Justyna Kalinowska-Tłuścik, Tomasz Lenda, Bogusław Pilarski, Andrzej J. Bojarski. Rationally designed N-phenylsulfonylindoles as a tool for the analysis of the non-basic 5-HT6R ligands binding mode. European Journal of Medicinal Chemistry, 2020, 209, 112916. DOI: 10.1016/j.ejmech.2020.112916. IF=5.573
  2. Jakub Staroń, Rafał Kurczab, Dawid Warszycki, Grzegorz Satała, Martyna Krawczyk, Ryszard Bugno, Tomasz Lenda, Piotr Popik, Adam S. Hogendorf, Agata Hogendorf, Krzysztof Dubiel, Mikołaj Matłoka, Rafał Moszczyński-Pętkowski, Jerzy Pieczykolan, Maciej Wieczorek, Paweł Zajdel, Andrzej J. Bojarski. Virtual screening-driven discovery of dual 5-HT6/5-HT2A receptor ligands with pro-cognitive properties. European Journal of Medicinal Chemistry, 2020, 185, 111857. DOI: 10.1016/j.ejmech.2019.111857. IF=5.573
  3. Linn M. Evenseth, Dawid Warszycki, Andrzej J. Bojarski, Mari Gabrielsen, Ingerbrigt Sylte. In Silico Methods for the Discovery of Orthosteric GABA(B) Receptor Compounds. Molecules, 2019, 24, 5. DOI: 10.3390/molecules24050935. IF=3.589
  4. Zahira Tber, Mylène Wartenberg, Jean-Eddy Jacques, Vincent Roy, Fabien Lecaille, Dawid Warszycki, Andrzej J. Bojarski, Gilles Lalmanach, Luigi A. Agrofoglio. Selective inhibition of human cathepsin S by 2,4,6-trisubstituted 1,3,5-triazine analogs. Bioorganic & Medicinal Chemistry, 2018, 26, 4310–4319. DOI: 10.1016/j.bmc.2018.07.032, IF=2.911
  5. Justyna Kalinowska-Tłuścik, Jakub Staroń, Anna Krawczuk, Stefan Mordalski, Dawid Warszycki, Grzegorz Satała, Adam S. Hogendorf, Andrzej J. Bojarski. The effect of the intramolecular C–HO interactions on the conformational preferences of bis-arylsulfones – 5 -HT6 receptor antagonists and beyond. RSC Advances., 2018, 8, 18672. DOI: 10.1039/c8ra03107j, IF=3.102
  6. Andrey V. Markov, Alexandra V. Sen’kova, Dawid Warszycki, Oksana V. Salomatina, Nariman F. Salakhutdinov, Marina A. Zenkova, Evgeniya B. Logashenko. Soloxolone methyl inhibits influenza virus replication and reduces virus-induced lung inflammation. Scientific Reports, 2017, 7: 13968. DOI:10.1038/s41598-017-14029-0, IF=4.847
  7. Dawid Warszycki, Marek Śmieja, Rafal Kafel. Practical application of the Average Information Content Maximization (AIC-MAX) algorithm: selection of the most important structural features for serotonin receptor ligands. Molecular Diversity, 2017, 21, 2, 407-412. DOI: 10.1007/s11030-017-9729-8. IF=1.966.
  8. Jakub Staroń, Stefan Mordalski, Dawid Warszycki, Grzegorz Satała, Adam Hogendorf, Andrzej J. Bojarski. Pyrano[2,3,4-cd]indole as a scaffold for selective nonbasic 5-HT6R ligands. ACS Medicinal Chemistry Letters, 2017, 8, 4, 390-394, DOI: 10.1021/acsmedchemlett.6b00482, IF=3.594.
  9. Thibaud Freyd, Dawid Warszycki, Stefan Mordalski, Andrzej J. Bojarski, Ingebrigt Sylte, Mari Gabrielsen. Ligand-guided homology modelling of the GABA(B2) subunit of the GABAB receptor. PLoS ONE, 2017, 12, 3, e0173889, DOI: 10.1371/journal.pone.0173889, IF=3.394.
  10. Dawid Warszycki, Manuel Rueda, Stefan Mordalski, Kurt Kristiansen, Grzegorz Satała, Krzysztof Rataj, Zdzisław Chilmonczyk, Ingebrigt Sylte, Ruben Abagyan, Andrzej J. Bojarski. From Homology Models to a Set of Predictive Binding Pockets-a 5-HT1A Receptor Case Study, Journal of Chemical Information and Modeling, 2017, 57, 2, 311-321. DOI: 10.1021/acs.jcim.6b00263, IF=4.066.
  11. Bessieres, M., Sari, O.; Roy, V.; Warszycki, D.; Bojarski, A.J., Nolan S.P.;, Snoeck, R.; Andrei, G.; Schinazi, R.F.; Agrofoglio, L. Sonication-Assisted Synthesis of (E)-2-Methyl-but-2-enyl Nucleoside Phosphonate Prodrugs, ChemistrySelect 2016, 1, 3108 – 3113
  12. Staroń, J.; Warszycki, D.;, Kurczab, R.; Satała, G.; Bugno, R.; Hogendorf, A.; Bojarski, A.J. Halogen bonding enhances activity in a series of dual 5-HT6/D2 ligands designed in a hybrid bioisostere generation/virtual screening protocol. RSC Advances, 2016, 6, 54918-54925 (http://pubs.rsc.org/en/content/articlelanding/2016/ra/c6ra08714k#!divAbstract)
  13. Śmieja, M.; Warszycki, D.;. Average Information Content Maximization—A New Approach for Fingerprint Hybridization and Reduction. PLoS One. 2016, Jan 11(1):e0146666
  14. Kucwaj-Brysz, K.; Warszycki, D.; Podlewska, S.; Witek, J.; Witek, K.; González Izquierdo, A.; Satała, G.; Loza, M.I.; Lubelska, A.; Latacz, G.; Bojarski, A.J.; Castro, M.; Kieć-Kononowicz, K.; Handzlik, J. Rational design in search for 5-phenylhydantoin selective 5-HT7R antagonists. Molecular modeling, synthesis and biological evaluation, Eur. J. Med. Chem., 2016, 112, 258-269 (http://www.ncbi.nlm.nih.gov/pubmed/26900658)
  15. Plebanek, E.; Chevrier, F.; Roy, V.; Garenne, T.; Lecaille, F.; Warszycki, D.; Bojarski, A.J.; Lalmanach, G.; Agrofoglio, L.A. Straightforward synthesis of 2,4,6-trisubstituted 1,3,5-triazine compounds targeting cysteine cathepsins K and S., Eur. J. Med. Chem., 2016, 121, 12-20 (http://www.ncbi.nlm.nih.gov/pubmed/27214508)
  16. Smusz, S.; Czarnecki, W. M.; Warszycki, D.; Bojarski, A. J. Exploiting uncertainty measures in compounds activity prediction using support vector machines. Bioorg. Med. Chem. Lett. 2015, 25, 100-105 (http://www.ncbi.nlm.nih.gov/pubmed/25466199)
  17. Warszycki, D.; Mordalski, S.; Staroń, J.; Bojarski, A.J. Bioisosteric matrices for ligands of serotonin receptors.  ChemMedChem. 2015 10, 601-605. (http://www.ncbi.nlm.nih.gov/pubmed/25772514)
  18. Staroń, J.; Warszycki, D.; Kalinowska-Tłuścik, J.; Satała, G.; Bojarski, A. J. Rational design of 5-HT6R ligands using a bioisosteric strategy: synthesis, biological evaluation and molecular modelling. RSC Advances 2015, 5, 25806-25815 (http://pubs.rsc.org/en/content/articlelanding/2015/ra/c5ra00054h#!divAbstract)
  19. Kurczyk, A.; Warszycki, D.; Musiol, R.; Kafel, R.; Bojarski, A.J.; Polanski, J. Ligand-Based Virtual Screening in a Search for Novel Anti-HIV-1 Chemotypes. J. Chem. Inf. Model. 201510, 2168-2177 (http://www.ncbi.nlm.nih.gov/pubmed/26431196).
  20. Śmieja, M.; Warszycki, D.; Tabor, J.; Bojarski A. J. Asymmetric clustering index in a case study of 5-HT1A receptor ligands. PLoS One 20149, e102069 (http://www.ncbi.nlm.nih.gov/pubmed/25019251)
  21. Warszycki, D.; Mordalski, S.; Kristiansen, K.; Kafel, R.; Sylte, I.; Chilmonczyk, Z.; Bojarski, A. J. A Linear Combination of Pharmacophore Hypotheses as a New Tool in Search of New Active Compounds – An Application for 5-HT1A Receptor Ligands. PLoS. One. 2013, 8, e84510 (http://www.ncbi.nlm.nih.gov/pubmed/24367669)
  22. Kaczor A; Reva, I.; Warszycki, D.; Fausto, R. UV-induced cyclization in myrcene isolated in rigid argon environment: FT-IR and DFT study. Journal of Photochemistry and Photobiology A: Chemistry. 2011, 222, 1-9 (http://www.sciencedirect.com/science/article/pii/S1010603011000694)

Participation in research projects:

  1. Creating an academia-based platform to discover substances acting on serotonergic or glutamatergic systems as potential new antidepressant or anxiolytic drugs. Project PNRF –103–AI-1/07 supported by a grant from Norway through the Norwegian Financial Mechanism within the Polish-Norwegian Research Fund (www.cns-platform.eu), 01.10.2010–31.06.2011, Function: executor.  

  2. Depression – mechanisms – therapy.
    Project co-financed by European Union from the European Fund of Regional Development (EFRD), WND-POIG.01.01.02-12-004/09-00, (www.de-me-ter.pl) , 01.07.2011–30.09.2014, Function: executor.

  3. Antagonists of 5-HT6 receptor as advanced antipsychotic drugs with pro-cognitive properties.
    Project co-financed by European Union from the European Fund of Regional Development (EFRD), UDA-POIG.01.03.01-12-063/09-02, (ProKog –www.prokog.pl), 01.07.2011–30.06.2013, Function: executor. 

  4. Allosteric modulation – new strategy in pharmacotherapy. Identification of the psychotropic roperties of glutamatergic receptor ligands of group III.
    Project co-financed by European Union from the European Fund of Regional Development (EFRD) WND-POIG.01.03.01-12-100/08,  01.07.2011–30.03.2013, Function: executor. 

  5. Innovative therapies for neurodegenerative and neurodevelopmental diseases based on mGlu receptor allosteric modulators. Project NCBiR 178469, 01.07.2013 ‒ 31.10.2016, Function: executor. 

  6. EXtention of academia-based PLATFORM to antidepressant hits discovery. Project Pol-Nor/198887/73/2013 supported by a grant from Norway through the Norwegian Financial Mechanism within the Polish-Norwegian Research Programme, (www.platformex.eu), 01.11.2013 ‒ 30.03.2016, Function: executor. 

  7.  

     Atypical 5-HT6 receptor ligands, Project NCN OPUS DEC-2014/3/B/NZ7/02210, 04.02.2015 – 03.08.2017, Function: executor, 2015-2017     

  8. Development of machine learning methods with implementation to prediction of chemical compounds activity, Project NCN PRELUDIUM DEC-2014/13/N/ST6/01832. 25.05.2015 ‒ 24.12.2016, Function: executor 
  9. A virtual screening protocol based on automatically generated structure-based pharmacophore models. Project NCN HARMONIA 2015/18/M/NZ2/00423, 12.04.2016 – 11.12.2020, Function: executor     
  10. Development of protocol for in silico design of compounds inhibit Ebola virus infection. Project NCN PRELUDIUM 2016/21/N/NZ2/01725, 27.01.2017-26.07.2018, Function: principal investigator
  11. Development of protocol for in silico design of compounds inhibit Ebola virus infection. Project NCN PRELUDIUM 2016/21/N/NZ2/01725, 27.01.2017-26.07.2018, Function: principal investigator
  12. Development of protocol for in silico design of compounds inhibit Ebola virus infection. Project NCN PRELUDIUM 2016/21/N/NZ2/01725, 27.01.2017-26.07.2018, Function: principal investigator
  13. Development of universal methods for data representation to improve the quality of machine learning methods with an example application in chemistry, Project PRELUDIUM Nr UMO-2016/21/N/ST6/01019, 14.03.2017 – 13.10.2019, Function: executor
  14. Polifarmakologiczna platforma skriningowa in silico, LIDER, LIDER/37/0137/L-9/17/NCBR/2018 supported by the Polish National Centre for Research and Development, 01.01.2019 – in progress, Function: executor 
  15. Amine derivatives of hydantoin as selective 5-HT7 receptor ligand. Molecular modeling, synthesis and pharmacological evaluation. Project NCN PRELUDIUM 2014/15/N/NZ7/03072, 21.09.2015 ‒ 20.03.2018, Function: executor
  16. 21.09.2015 ‒ 20.03.2018, Function: executorComputer-aided searching for the MurD ligase as an antibacterial agentsProject Polish Ministry of Science and Higher Education DN/MOB/303/IV/2015, 15.11.2015 – 15.04.2016, Function: principal investigator

Scientific reports:

a) posters:

  1. Dawid Warszycki, Łukasz Struski,Marek Śmieja, Rafał Kafel, Rafał Kurczab. Combination of pharmacophore fingerprint and artificial intelligence as a new approach in search for GPCR ligands, March 28-30, Stambul, Turkey (conference online due to the covid outbreak)
  2. Dawid Warszycki, Linn M. Evenseth, Andrzej J. Bojarski Lessons learned from docking with the presence of water molecules – does it worth it?, GPCR Workshop, December 5-9, 2017, Kailua-Kona, USA
  3. Dawid Warszycki, Vincent Roy, Luigi Agrofoglio, Andrzej J. Bojarski Development of the virtual screening cascade in search for inhibitors of Niemann-Pick C1 protein as a anti Ebola agents. 13th German Conference on Chemoinformatics, November 6-8, 2017, Mainz, Germany
  4. Dawid Warszycki, Vincent Roy, Luigi Agrofoglio, Andrzej J. Bojarski Application of the novel pharmacophore modelling methodology in search for Ebola virus inhibitors. III Sympozjum Chemii Medycznej, September 6-8, 2017, Wrocław, Poland
  5. Dawid Warszycki, Christian Munk, David E. Gloriam, Rafał Kafel, Andrzej J. Bojarski, Stefan Mordalski Structure-based pharmacophore models as a tool for template assessment for homology modeling , GLISTEN meeting, March 29-31, 2017, Porto, Portugal
  6.  Freyd, T.; Evenseth, L.M.; Wushur, I.; Gabrielsen, M.; Warszycki, D.; Mordalski, S.; Brański, P.;Chruścicka, B.; Burnat, G.; Pilc, A.; Bojarski, A.J.; Sylte, I.; Screening for new GABAB receptor compounds; Glisten 2016 Prague, 26-27.09.2016, Prague, Czech Republic, Book of Abstracts Abstract
  7. Warszycki, D.; Rataj, K.; Gloriam, D.E.; Bojarski, A.J.; Mordalski, S.; Selection of the most significant ligand-receptor interactions in GPCRs crystal complexes; Glisten 2016 Prague, 26-27.09.2016, Prague, Czech Republic, Book of Abstracts Abstract Poster
  8.  Freyd, T.; Warszycki, D.; Gabrielsen, M.; Mordalski, S.; Bojarski, A.J.; Sylte, I.; Allosteric modulation of the human GABAB receptor; VIIIth Conversatory on Medicinal Chemistry, 15-17.09.2016, Lublin, Poland, Book of Abstracts, p.P118 Abstract Poster
  9. Bugno, R.; Staroń, J.; Hogendorf, A.S.; Satała, G.; Warszycki, D.; Mordalski, S.; Bojarski, A.J.; Synthesis and evaluation of a new indole-based series as nonbasic 5-HT6 receptor ligands; VIIIth Conversatory on Medicinal Chemistry, 15-17.09.2016, Lublin, Poland, Book of Abstracts, p.P95 Abstract Poster
  10. Warszycki, D.; Agrofoglio, L.; Roy, V.; Bojarski, A.J. ; Application of linear combination of pharmacophore models in modeling and screening of UDP-N-acetylmuramoylalanine glutamate ligase inhibitors; VIIIth Conversatory on Medicinal Chemistry, 15-17.09.2016, Lublin, Poland, Book of Abstracts, p.P33 Abstract Poster
  11. Staroń, J.; Warszycki, D.; Kurczab, R.; Satała, G.; Kalinowska-Tłuścik, J.; Bojarski, A.J.;Serendipity discoveries in medicinal chemistry; a case of 5-HT6R ligands. Bioisosterism, organic synthesis, crystal structures and molecular modelling.; 3rd EFMC Young Medicinal Chemist Symposium, 28.08.01.09.2016, Manchester, United Kingdom, Book of Abstracts
  12. Staroń, J.; Satała, G.; Warszycki, D.; Bojarski, A.J.; A non-basic 5-HT6R antagonists; XXIV EFMC International Symposium on Medicinal Chemistry, 28.08.01.09.2016, Manchester, United Kingdom, Book of Abstracts
  13. Bugno, R.; Strekowska, A.; Hogendorf, A.S.; Satała, G.; Warszycki, D.; Mordalski, S.;Bojarski, A.J.; Design, synthesis and structure-activity relationships of 1-(arylsulfonyl)-1H-indole derivatives as non-basic 5-HT6 receptor ligands;  XXIV EFMC International Symposium on Medicinal Chemistry, 28.08.01.09.2016, Manchester, United Kingdom, Book of Abstracts
  14. Warszycki, D.; Roy, V. ; Bojarski, A.J.; Agrofoglio, L.; Virtual screening cascade in search for novel purine-derivated Mur D inhibitors as antibacterial agents; 22 International Round Table on Nucleosides, Nucleotides and Nucleic Acids (XXII IRT), 18-22.07.2016, Paris, France, Book of Abstracts Abstract Poster
  15. Staroń, J.; Kurczab, R.; Warszycki, D.; Satała, G.; Bugno, R.; Hogendorf, A.; Bojarski, A.J.;Halogen bonding enhances affinity at 5-HT7R in a series of N-[2-(dimethylamine)ethyl]-N-(2-phenylehtyl)anilines; 2nd Central European Biomedical Congress (CEBC), 15-18.06.2016, Kraków, Poland, Book of Abstracts, p.135
  16. Warszycki, D.; Roy, V. ; Agrofoglio, L.; Bojarski, A.J.; Pharmacophore modeling of UDP-N-acetylmuramoylalanine glutamate ligase inhibitors – methodology and application for virtual screening procedure; 2nd Central European Biomedical Congress (CEBC), 15-18.06.2016, Kraków, Poland, Book of Abstracts, p.41
  17. Warszycki, D.; Smieja, M.; Bojarski, A.J.; Tabor, J.; Mean Information Content (MIC) algorithm – a new approach for fingerprint hybridization and reduction; 11th German Conference on Chemoinformatics, 08-10.11.2015, Fulda, Germany, Book of Abstracts, p.P24
  18. Podlewska, S.; Warszycki, D.; Bojarski, A.J.; Because two is always better than one – towards the search of dual 5-HTx-SERT ligands ; GLISTEN Meeting Amsterdam 2015, 12-13.10.2015, Amsterdam, The Netherlands, Book of Abstracts, p.25 Abstract Poster
  19. Warszycki, D.; Kafel, R.; Bojarski, A.J.; Application of linear combination of pharmacophore hypotheses into search for the dual 5-T1A/SERT ligands; GLISTEN Meeting Amsterdam 2015, 12-13.10.2015, Amsterdam, The Netherlands, Book of Abstracts, p.36 Abstract Poster
  20. Bugno, R.; Staroń, J.; Hogendorf, A.; Satała, G.; Warszycki, D.; Mordalski, S.; Bojarski, A.J.; Non-basic 5-HT6 Receptor Ligands; VIIth Conversatory on Medicinal Chemistry; VIIth Conversatory on Medicinal Chemistry, 17-19.09.2015, Lublin, Poland, Book of Abstracts, p.PP7 Abstract Poster
  21. Warszycki, D.; Rataj, K.; Bojarski, A.J.; An analysis of molecular interactions between the 5-HT6 receptor and non-basic ligands; VIIth Conversatory on Medicinal Chemistry, 17-19.09.2015, Lublin, Poland, Book of Abstracts, p.P102 Abstract Poster
  22. Staroń, J.; Warszycki, D.; Satała, G.; Bojarski, A.J.; Derivatives of N-[2-(dimethylamine)ethyl]-N-(2-phenylethyl)-aniline as potential polypharmacological ligands of SERT/5-HT6/5-HT7; VIIth Conversatory on Medicinal Chemistry, 17-19.09.2015, Lublin, Poland, Book of Abstracts, p.P92 Abstract Poster
  23. Hogendorf, A.; Bugno, R.; Satała, G.; Hogendorf, A.; Staroń, J.; Warszycki, D.; Bojarski, A.J.; Design and synthesis of aminergic GPCR’s ligands; Naukowe Doktorantów III Edycja, 18.04.2015, Kraków, Poland, Book of Abstracts, p.24 Abstract
  24. Hogendorf, A.; Satała, G.; Staroń, J.; Hogendorf, A.; Bugno, R.; Warszycki, D.; Bojarski, A.J.; Three point pharmacophore investigation leads to novel serotonergic chemotypes; GLISTEN Spring Meeting 2015, 01-02.04.2015, Allschwil, Switzerland, Book of Abstracts, p.44
  25. Kucwaj-Brysz, K.; Warszycki, D.; Witek, J.; Smusz, S.; Satała, G.; Bojarski, A.J.; Handzlik, J.; Kieć-Kononowicz, K.; Hydantoin derivatives as selective serotonin 5-HT7 receptor ligands; The GLISTEN Budapest 2014 Conference, 02-04.10.2014, Budapest, Hungary, Book of Abstracts, p.P416 Abstract
  26. Warszycki, D.; Mordalski, S.; Freyd, T.; Sylte, I.; Bojarski, A.J.; Pharmacophore modeling of GABA-B receptor ligands – methodology and application for virtual screening; The GLISTEN Budapest 2014 Conference, 02-04.10.2014, Budapest, Hungary,  Book of Abstracts, p.P407 Abstract Poster
  27. Warszycki, D.; Staroń, J.; Kafel, R.; Bojarski, A.J.; Lessons learned from analysis of bioisosteric substitution in ligands of serotonin receptor family; VIth Conversatory on Medicinal Chemistry, 18-20.09.2014, Lublin, Poland, Book of Abstracts, p.188 Abstract Poster
  28. Staroń, J.; Warszycki, D.; Kalinowska-Tłuścik, J.; Satała, G.; Bojarski, A.J.; Investigation of Ligand Binding Mode at 5-HT6R with the Use of Bioisosterism ; The XXIII International Symposium on Medicinal Chemistry (EFMC-ISMC 2014), 07-11.09.2014, Lisbon, Portugal, Book of Abstracts, p.129 Abstract Poster
  29. Freyd, T.; Warszycki, D.; Gabrielsen, M.; Kristiansen, K.; Chilmonczyk, Z.; Bojarski, A.J.;Sylte, I.; Allosteric modulation of the human GABAB receptor: Development of a tool for antidepressant drug discovery; The 5th Annual BioStruct Conference, 28-31.08.2014, Jagtvolden, Norway,  Book of Abstracts, p.22 Abstract
  30. Warszycki, D.; Staroń, J.; Kafel, R.; Bojarski, A.J.; Comprehensive analysis of bioisosteric replacement in ligands of a serotonin receptors family; The 10th International Conference on Chemical Structures, 01-05.06.2014, Noordwijkerhout, the Netherlands,  Book of Abstracts, p.90 Abstract
  31. Kucwaj-Brysz, K.; Warszycki, D.; Satała, G.; Bojarski, A.J.; Handzlik, J.; Kieć-Kononowicz, K.; Poszukiwanie selektywnych ligandów receptora serotoninowego 5-HT7 pośród aminoalkilowych pochodnych hydantoiny; 29-30.05.2014, Kraków, Polska, Zeszyty Naukowe Towarzystwa Doktorantów UJ, Nr 8, p.118 Abstract
  32. Freyd, T.; Warszycki, D.; Gabrielsen, M.; Mordalski, S.; Kristiansen, K.; Chilmonczyk, Z.;Bojarski, A.J.; Sylte, I.; Allosteric modulation of the human GABA B receptor; GPCR Structure, Function and Drug Discovery Conference, 19-26.05.2014, Cambridge, USA,  Book of Abstracts
  33. Smusz, S.; Czarnecki, W.; Warszycki, D.; Bojarski, A.J.; Uncertainty of the in vitro experiments in the predictive models construction; GPCR Spring Conference 2014, 28-30.04.2014, Barcelona, Spain, Book of Abstracts, p.32 Poster
  34. Warszycki, D.; Rueada, M.; Kristiansen, K.; Sylte, I.; Abagyan, R.; Bojarski, A.J.; Ligand binding mode analysis using new 5-HT1A receptor models developed by ALiBERO methodology; GPCR Spring Conference 2014, 28-30.04.2014, Barcelona, Spain,  Book of Abstracts, p. 23 Poster
  35. Warszycki, D.; Rueada, M.; Kristiansen, K.; Sylte, I.; Abagyan, R.; Bojarski, A.; From homology models on raw templates to a set of ALiBERO binding pockets – a 5-HT1A receptor case study; GPCR-Ligand Interactions, Structures, and Transmembrane Signalling: a European Research Network, 07-09.10.2013, Warsaw, Poland, Poster
  36. Staroń, J.; Warszycki, D.; Kalinowska-Tłuścik, J.; Satała, G.; Bojarski, A.J.; The use of bioisosteric strategy to design and analyse 5-HT6 ligands binding mode;  III Konferencja Naukowa Doktorantów Wydziału Lekarskiego i Farmaceutycznego UJ CM, 09-10.05.2013, Zeszyty Naukowe Towarzystwa Doktorantów Uniwersytetu Jagiellońskiego, Nauki Ścisłe, Nr 6 (1/2013), p.164. Poster
  37. Kurczyk, A.; Warszycki, D.; Kafel, R.; Musioł, R.; Bojarski, A.J.; Polański, J.; Development of Multistep Ligand-Based Virtual Screening Cascade Methodology in a Search for Novel HIV-1 Integrase nhibitors: 1. Machine Learning; The 5th Conversatory of Medicinal Chemistry, 13-15.09.2012, Lublin, Poland, Book of Abstracts, p.P-33.Abstract
  38. Kurczab, R.; Warszycki, D.; Bojarski, A.J.; The Novel Approach in Structure-Based 3D Pharmacophore Model Generation. An Application to Searching for 5-HT6R Selectivity Hypothesis; The 5th Conversatory of Medicinal Chemistry, 13-15.09.2012, Lublin, Poland, Book of Abstracts, p.P-32. Abstract Poster
  39. Warszycki, D.; Kurczyk, A.; Kafel, R.; Musioł, R.; Bojarski, A.J.; Polański, J.; Development of Multistep Ligand-Based Virtual Screening Cascade Methodology in a Search for Novel HIV-1 Integrase Inhibitors: 2. Privileged Fragments; The 5th Conversatory of Medicinal Chemistry, 13-15.09.2012, Lublin, Poland, Book of Abstracts, p.C-7. Abstract Poster
  40. Warszycki, D.; Satała, G.; Staroń, J.; Bojarski, A.J.; Bioisosteric replacement in search for novel 5-HT6R ligands; 5th Symposium of the Polish Bioinformatics Society, 25-27.05.2012, Gdańsk, Poland, Book of Abstracts, p.Talk19. Abstract Poster
  41. Warszycki, D.; Kristiansen, K.; Kurczab, R.; Mordalski, S.; Sylte, I.; Bojarski, A.J.; Linear Combination of Pharmacophore Hypotheses as a New Tool in Search of New 5-HT1A Receptor Ligands; The 4th Conversatory of Medicinal Chemistry, 08-10.09.2011, Lublin, Poland, Book of Abstracts, p.PP-4. Abstract Poster
  42. Staroń, J.; Warszycki, D.; Satała, G.; Bugno, R.; Bojarski, A.J.; Bioisosterism, the use in designing 5-HT6 receptor ligands; 4th International Symposium on Advances in Synthetic and Medicinal Chemistry, 21-25.08.2011, St. Petersburg, Russia, Book of Abstracts, p.176. Abstract Poster
  43. Warszycki, D.; Kristiansen, K.; Kurczab, R.; Satała, G.; Mordalski, S.; Sylte, I.; Bojarski, A.J.; Extensive pharmacophore modeling studies on 5-HT1A receptor ligands – single hypothesis vs. linear combinations; VII Joint Meeting on Medicinal Chemistry, 26-27.06.2011, Catania, Italy, Book of Abstracts, p.186. Abstract Poster
  44. Warszycki, D.; Kristiansen, K.; Mordalski, S.; Kurczab, R.; Sylte, I.; Bojarski, A.J.; Comparison of various strategies in pharmacophore models generation – application to 5-HT1A receptor ligands; 9th International Conference on Chemical Structures, 05-09.06.2011, Noordwijkerhout, The Netherlands, Book of Abstracts, p.95. Abstract Poster
  45. Kristiansen, K.; Rueada, M.; Warszycki, D.; Kurczab, R.; Gabrielsen, M.; Abagyan, R.; Bojarski, A.J.; Sylte, I.; Modeling of ligand interactions for the human 5-HT1A receptor. Docking, pharmacophores and virtual screening of databases containing drug-like compounds; The 47th Norwegian Biochemical Society (NBS) contact meeting, 03-06.02.2011, Norway, Book of Abstracts, p.108. Abstract
  46. Smusz, S.; Kurczab, R.; Warszycki, D.; Kościółek, T.; Mordalski, S.; Bojarski, A.J.; Hybridization of ligands as a way of generating combinatorial libraries of drug candidates; Spring Congress of Polish Chemical Society Student Section, 13-17.04.2011, Murzasichle, Poland, Book of Abstracts, p.130. Abstract Poster
  47. Prymula, K; Kościółek, T.; Kurczab, R.; Mordalski, S.; Satała, G.; Warszycki, D. Bojarski, A.J.; New strategy for use of pharmacophore models in virtual screening for 5-HT6 receptor ligands, The 3rd Conversatory of Medicinal Chemistry, September 20–22, 2010, Lublin, Poland

b) speeches:

  1. Warszycki, D.; Kurczyk, A.; Kafel, R.; Musioł, R.; Bojarski, A.J.; Polański, J.; Development of Multistep Ligand-Based Virtual Screening Cascade Methodology in a Search for Novel HIV-1 Integrase Inhibitors: 2. Privileged Fragments; The 5th Conversatory of Medicinal Chemistry, 13-15.09.2012, Lublin, Poland, Book of Abstracts, p.C-7. Abstract Poster
  2. Warszycki, D.; Satała, G.; Staroń, J.; Bojarski, A.J.; Bioisosteric replacement in search for novel 5-HT6R ligands; 5th Symposium of the Polish Bioinformatics Society, 25-27.05.2012, Gdańsk, Poland, Book of Abstracts, p.Talk19. Abstract Poster
  3. Warszycki, D.; Kristiansen, K.; Kurczab, R.; Mordalski, S.; Sylte, I.; Bojarski, A.J.; Linear Combination of Pharmacophore Hypotheses as a New Tool in Search of New 5-HT1A Receptor Ligands; poster presentation, The 4th Conversatory of Medicinal Chemistry, 08-10.09.2011, Lublin, Poland, Book of Abstracts, p.PP-4. Abstract Poster
  4. Warszycki, D.; Prymula, K.; Kurczab, R.; Satała, G.; Bojarski, A.J.; The Implementation of an Expert System to Search for Novel Substances Acting on Serotonergic and Glutamatergic Systems; 3rd Conversatory of Medicinal Chemistry, September 20–22, 2010, Lublin, Poland, Book of Abstracts, p.K-3. Abstract

Experience gained in Poland:

Institute of Catalysis and Surface Chemistry Polish Academy of Sciences Cracow – Department of Zeolite Chemistry I, 16.07.2009 – 14.08.2009 (student practice)

Experience gained abroad:

  • France, Institute di Chimie Organique et Analityque,University of Orleans, 15.09.2009-15.03.2010
  • Norway, Medical Pharmacology and Toxicology, Department of Medical Biology, Faculty of Health Science, University of Tromsø, 14-22.11.2010
  • Norway, Medical Pharmacology and Toxicology, Department of Medical Biology, Faculty of Health Science, University of Tromsø, 12-21.09.2011
  • France, Institute di Chimie Organique et Analityque,University of Orleans, 25.05-02.06.2012
  • France, Institute di Chimie Organique et Analityque,University of Orleans, 02-05.12.2012
  • France, Institute di Chimie Organique et Analityque,University of Orleans, 16.11.2015-15.04.2016
  • 26.04.2017 – 09.05.2017, Norway, UiT The Arctic University of Norway, Faculty of Health Sciences, Department of Medicinal Biology, research visit
  • 17.05.2017-17.06.2017, France, Universited’Orleans, Institute de Chimie Organique at Analityque, research visit 
  • 27.09.2017-27.10.2017, France, Universited’Orleans, Institute de Chimie Organique at Analityque, research visit