Publications 2012

1. Obniska, J.; Chlebek, I.; Kamiński, K.; Bojarski, A. J.; Satała, G. Synthesis, anticonvulsant activity and 5-HT1A/5-HT7 receptors affinity of 1-[(4-arylpiperazin-1-yl)-propyl]-succinimides. Pharmacol. Rep. 2012, 64, 326-336 (http://www.ncbi.nlm.nih.gov/pubmed/22661183)
2. Tokarski, K.; Zelek-Molik, A.; Duszynska, B.; Satała, G.; Bobula, B.; Kusek, M.; Chmielarz, P.; Nalepa, I.; Hess, G. Acute and repeated treatment with the 5-HT7 receptor antagonist SB 269970 induces functional desensitization of 5-HT7 receptors in rat hippocampus. Pharmacol. Rep. 2012, 64, 2556-65 (http://www.ncbi.nlm.nih.gov/pubmed/22661174)
3.  Marciniec, K.; Maslankiewicz, A.; Maslankiewicz, M. J.; Kurczab, R. Synthesis, 15N NMR spectra and GIAO calculated data of the seven positional isomers of 15N-labeled N,N-dimethylsulfamoylquinoline. J. Mol. Struc. 20121015, 46-50
(http://www.sciencedirect.com/science/article/pii/S0022286012000890)
4. Valkova, I.; Zlatkov, A.; Nedza, K.; Doytchinova, I. Synthesis, 5-HT1A and 5-HT2A receptor affinity and QSAR study of 1-benzhydryl-piperazine derivatives with xanthine moiety at N4. Med. Chem. Res. 2012, 21, 477-486 (http://link.springer.com/article/10.1007%2Fs00044-011-9555-y)
5. Zajdel, P.; Marciniec, K.; Maslankiewicz, A.; Satala, G.; Duszynska, B.; Bojarski, A. J.; Partyka, A.; Jastrzebska-Wiesek, M.; Wrobel, D.; Wesolowska, A.; Pawlowski, M. Quinoline- and isoquinoline-sulfonamide derivatives of LCAP as potent CNS multi-receptor-5-HT1A/5-HT2A/5-HT7 and D2/D3/D4-agents: the synthesis and pharmacological evaluation. Bioorg. Med. Chem. 2012, 20, 1545-1556 (http://www.ncbi.nlm.nih.gov/pubmed/22277589)
6. Jaronczyk, M.; Wolosewicz, K.; Gabrielsen, M.; Nowak, G.; Kufareva, I.; Mazurek, A. P.; Ravna, A. W.; Abagyan, R.; Bojarski, A. J.; Sylte, I.; Chilmonczyk, Z. Synthesis, in vitro binding studies and docking of long-chain arylpiperazine nitroquipazine analogues, as potential serotonin transporter inhibitors. Eur. J. Med. Chem. 2012, 49C, 200-210
(http://www.ncbi.nlm.nih.gov/pubmed/22309909)
7. Witowska-Jarosz, J.; Jaronczyk, M.; Mazurek, A. P.; Sylte, I.; Bojarski, A. J.; Chilmonczyk, Z.; Jarosz, M. Mass-spectrometric studies of new 6-nitroquipazines-serotonin transporter inhibitors. Anal. Bioanal. Chem. 2012, 402, 537-541
(http://www.ncbi.nlm.nih.gov/pubmed/21960253).
8. Gabrielsen, M.; Kurczab, R.; Ravna, A. W.; Kufareva, I.; Abagyan, R.; Chilmonczyk, Z.; Bojarski, A. J.; Sylte, I. Molecular mechanism of serotonin transporter inhibition elucidated by a new flexible docking protocol. Eur. J. Med. Chem. 2012, 47, 24-37
(http://www.ncbi.nlm.nih.gov/pubmed/22071255).
9. Zajdel, P.; Kurczab, R.; Grychowska, K.; Satała, G.; Pawłowski, M.; Bojarski, A. J. The multiobjective based design, synthesis and evaluation of the arylsulfonamide/amide derivatives of aryloxyethyl- and arylthioethyl- piperidines and pyrrolidines as a novel class of potent 5-HT7 receptor antagonists. Eur. J. Med. Chem. 2012, 56, 348-360
(http://www.ncbi.nlm.nih.gov/pubmed/22926225).